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CAS 107868-30-4 Anti Estrogen Fat Loss Steroids Aromasin / Exemestane Oral Anabolic Steroids

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CAS 107868-30-4 Anti Estrogen Fat Loss Steroids Aromasin / Exemestane Oral Anabolic Steroids

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USPSTAR Technology Co.,Limited

Verified Supplier

HONG KONG

Business type: Manufacturer, Exporter, Trading Company

Telephone : 86-131-6600-1147

No49 Hollywood road, Central, Hilltop Plaza Hong Kong

Product Details:

Place of Origin: HONG KONG
Brand Name: DV-Labs
Certification: GMP
Model Number: 107868-30-4

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiation
Packaging Details: Discreet ways of packing for Customs pass guaranteed
Delivery Time: Delivery within 24h after payment
Payment Terms: Western Union
Supply Ability: 500kg/month
Detailed Product Description
Product Name: Exemestane Assay: 99%
Quality Standards: USP26 Appearance: White Or Almost White Crystalline Powder
Shipping Out: In 24 Hours After Confirm Payment Email: Service_TS@126.com

CAS 107868-30-4 Anti Estrogen Steroids Aromasin / Exemestane Oral Anabolic Steroids

 

 

Specifications


Product name: Exemestane
Alias: Aromasin Exemestan;Exemestane Aromasin Powder ; Exemestane Powder
CAS: 107868-30-4
Assay: 98%-102%.
MF: C20H24O2
MW: 296.4
Character: White crystalline powder,
MP: 155.13C.

 

 

Product Description

 

Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.

 

The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system.

Applications:

Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition." By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen.

Exemestane is taken in tablet form once a day. Patients can experience side effects like nausea, anxiety, shortness of breath, abdominal pain, bone pain, and chest pain. Side effects vary widely between patients and patients should report the side effects they experience to their doctors, as some may be indicators of dangerous complications. Shortness of breath and chest pain in particular are causes for concern in patients taking exemestane.

 

 

Application:

 

Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.

 

The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system.

 

Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition." By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen.

 

Exemestane is taken in tablet form once a day. Patients can experience side effects like nausea, anxiety, shortness of breath, abdominal pain, bone pain, and chest pain. Side effects vary widely between patients and patients should report the side effects they experience to their doctors, as some may be indicators of dangerous complications. Shortness of breath and chest pain in particular are causes for concern in patients taking exemestane.

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